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People suffering from insomnia may have a higher risk of coronary artery ailment, heart failure, and stroke, suggests a study. The study was published in the journal-Circulation. Previous observational studies have found an association between insomnia, which affects up to 30 per cent of the general population, and an increased risk of developing heart disease and stroke. However, the observational studies were unable to determine whether insomnia is a cause, or if it is just associated with them. In this first-of-its-kind study on insomnia, Larsson and a colleague applied Mendelian randomisation, a technique that uses genetic variants known to be connected with a potential risk factor such as insomnia, to reduce bias in the results. The 1.3 million participants with or without heart disease and stroke were drawn from four major public studies and groups. Researchers found genetic variants for insomnia were associated with significantly higher odds of coronary artery disease, heart failure, and ischemic stroke, particularly large artery stroke, but not atrial fibrillation.